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Writer's picturemeowdini
May 212 min read

Sticking with the Shot: GLP-1s for Weight Loss Require Long-Term Commitment

New research reveals challenges with GLP-1 medication adherence for weight management.

GLP-1 receptor agonists, like Wegovy, have become popular for weight loss, but a recent study raises concerns about treatment discontinuation.



The analysis, based on insurance data, shows that a significant portion (58%) of patients stop using GLP-1 medications within 12 weeks.

This falls short of the recommended treatment duration for assessing weight loss effectiveness.

Over 30% discontinue treatment within the first four weeks, before reaching the targeted dose.


Reasons for Early Discontinuation:

  • Impatience with results: Two-thirds of those who used injectable weight-loss drugs perceive them as effective, but this sentiment drops significantly among those who stopped treatment.

  • Side effects: Nausea, diarrhea, vomiting, and constipation are common in the initial stages and can deter patients.

The Importance of Long-Term Management:

  • Experts emphasize that GLP-1s are for chronic weight management, requiring a long-term commitment.

  • Regular follow-up appointments are crucial for managing side effects, adjusting expectations, and monitoring progress.


Individualized Approach is Essential:

  • Each person responds differently to treatment. Balancing cost, benefits, and individual needs is vital.


The Role of Healthcare Providers:

  • The study highlights the crucial role of doctors in supporting patient adherence.

  • More frequent check-ins and addressing specific needs can significantly increase the chances of staying on track.

  • Prescriptions from specialists like endocrinologists may lead to improved treatment persistence.


Focus on Overall Support:

  • Wrap-around services like lifestyle coaching, nutritional guidance, and side effect management are key to success.

  • Addressing social determinants of health, like access to healthy food and transportation, is also crucial.




GLP-1 medications hold promise for weight management, but long-term commitment and comprehensive support from healthcare providers are essential for optimal outcomes.



Source: CNN

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